EcoCyc
Originally a database on metabolic pathways in Escherichia coli
Currently being extended to other microbial organisms. MetaCyc (no genomic data)
Pathway diagrams have been generated with the aid of a graph layout algorithm, & stored as static images for web browsing.
Based on published experimental data, and unlike KEGG, also includes information about genes that have not yet been cloned but whose function has been characterised by genetic and biochemical approaches.