Transcriptional Regulation
metA
Homoserine-O- succinyltransferase
expression
Down -regulation
PHO5
Pho5p
expression
up-regulation
Transcriptional activation (up-regulation)
Transcriptional repression (down-regulation)
Pho4p
Methionine Holorepressor
Protein -o [up-regulates] -> expression
Protein -o [down-regulates] -> expression
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