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Dr. Carola S. König
Dipl.-Ing., Ph.D., PGCert, CEng, MIMechE, FHEA
Senior Lecturer
& Flood and Coastal Engineering Programme Lead & Course Director
Academic Qualifications
1992
Dipl.-Ing., Maschinenwesen
(Mechanical Engineering), University of Stuttgart, Germany
1998
Ph.D., Dept. of Manufacturing & Engineering Systems, Brunel University
2008 PGCert,
Post Graduate Certificate for Teaching and Learning in Higher Education, Brunel
University
Employment
1991/1992
Research Centre, Daimler-Benz, Stuttgart, Germany
1997-1999
Dept. of Manufacturing & Engineering Systems, Brunel University
1999-2001
Dept. of Mechanical Engineering, Brunel University
2001-to date Institute for Bioengineering, Brunel University
Research Interests
Research area covers both experimental and computational fluid mechanics as well as biomedical engineering. Main research interest lies in computational fluid mechanics with particular activities in both biomedical and industrial flows. Extensive work was undertaken on blood flow modelling through a ventricular assist device. Subsequent research involved the modelling of plume flows in connection with chemical reaction modelling. Current research activity involves experimental and numerical two-phase flow modelling related to countercurrent chromatography (CCC) as well as microcirculation flows.
Selected Conference Papers and Lectures
König, C., Clark, C., Mokhtarzadeh R. (1995) 'Modelling of flow in a ventricular assist device, including the problem of a moving boundary'. In: Workshop on Computational Fluid Dynamics in the Cardiovascular System, University of Leeds, 11 January.
König, C. (1996) 'Strömungssimulation an einem Modell einer künstlichen Herzpumpe - Flow simulation in a model of an artificial heart-pump'. Invited evening lecture in German at The Institution of Electrical Engineers, London, 23 January.
Fabbri, G., Long, Q., König,
C.S., Gao, H., Collins, M. Pinelli , M. (2007) 'Stress calculations for different degrees of
carotid arterial stenosis using 3-dimensional fluid-structure interaction
models '. In: 4th Physiological Flow Network Meeting: Respiratory Mechanics
and Physiological Fluid-Structure Interaction Problems, Univeristy
of Manchester, 2-3 April.
Wu, J., Xu,
S., Long, Q., Collins, M., König, C., Zhao, G., Jiang, Y., Padhani,
A. (2007). 'Simulation of microcirculation in solid tumors
'. In: IEEE/ICME Int. Conference on Complex Medical Engineering, 23-27 May
2007, pp. 1555-1562.
Fabbri, G., Long, Q., Gao, H.,
König, C., Collins, M., Pinelli , M. (2007) 'Stress analysis of carotid arterial
stenosis with 3-D fluid-structure interaction simulations '. In: ASME
Summer Bioengineering Conference, 20-24 June, Keystone, CO, USA.
Luppi, L., Long, Q., König,
C., Collins, M. (2007) 'Numerical study of blood redistribution in the
circle of Willis of patients with carotid artery stenosis '. In: ASME
Summer Bioengineering Conference, 20-24 June, Keystone, CO, USA.
Wu, J., Xu,
S., Long, Q., Collins, M., König, C., Zhao, G., Jiang, Y., Padhani,
A. (2007) 'Simulation of blood perfusion in tumour mircovasculature
'. In: ASME Summer Bioengineering Conference, 20-24 June, Keystone, CO,
USA.
König, C.S.
(2007). 'Correlations between art and CFD through colour and shape '.
In: Colour and Design II, Colour in plants and animals: inspiration for design,
22&23 November 2007, London, UK
Swalen,
M.J.P., König, C.S., Khir, A.W., Sayma, A.I. (2008).
'Development of a novel ventricular assist device (VAD) '. In: ESAO
2008, XXXV Annual Meeting of the European Society of Artificial Organs, 3-6
September 2008, Genva,
Switzerland.
König, C.S.
& Collins, M.W. (2008). 'Goethe, Eastlake and Turner: from colour theory
to art '. In: Colour, Art and Nature, Edinburgh, 24 October
Pontrelli, G., König, C.S.,
Collins, M.W., Long, Q., Succi, S. (2009). 'Modelling
wall shear stress in small arteries using LBM and FVM '. Paper submitted
for the 2nd Micro and Nano Flows Conference, 1&2 Spetember
2009, Brunel University, Uxbridge, UK.
Swalen, M.J.P.,
König, C.S., Sayma, A.I., Khir, A.W. (2009). 'Computational
study of a novel axial flow pump as LVAD '. In: ESAO 2009, XXXVI Annual
Meeting of the European Society of Artificial Organs, 2-5 September 2009, Technical University of Compiegne, France.
Patel, K.N.,
König, C.S., Sayma, A.I., Khir, A.W. (2009). 'Transient
behaviour of different impeller designs of a pulsatile axial flow LVAD: a
computational study '. In: ESAO 2009, XXXVI Annual Meeting of the European
Society of Artificial Organs, 2-5 September 2009, Technical
University of Compiegne, France.
König, C.S.,
Collins, M.W., Harkness, N. (2009). 'Colour and mood: from Goethe's colour
theory to interior and garden design '. Paper submitted for the 11th
Congress of the Int. Colour Associaion (AIC) 2009, 27
Sept. - 2 Oct. 2009, University of New South Wales, Sydney,
Australia.
Collins, M.W.,
König, C.S., Atherton, M. (2009). 'Wall shear stress and arterial
performance: two approaches based on engineering '. In: Bioengineering 24
& 25 Sept. 2009, University of Oxford, Oxford, UK.
van den Heuvel, R., König,
C.S. (2010). 'Real "g"-level calculations of all coil planet
centrifuges '. In: CCC 2010, 6th International Symposium on Countercurrent Chromatography, 28-30 July 2010, Villeubanne, France.
Swalen,
M.J.P., König, C.S., Sayma, A.I., Khir, A.W. (2010).
'CFD modelling of a bi-directional VAD impeller supporting blood flow
towards the ventricle and periphery '. Submitted for ESAO 2010, XXXVII
Annual Meeting of the European Society of Artificial Organs, 8-11 September
2010, Skopje, R. Macedonia.
König, C.S.,
van den Heuvel, E., Jowitt, F., Collins, M.W., Gilhooly, M. (2010). 'Ageing
and Lifestyle: some UK approaches'. Lifestyle and Ageing, 4-5 October 2010,
Pisa, Italy.
Halliday, I., Pontrelli, G., Spencer, TJ, Care, C.M., König, C.S.,
Collins, M.W., (2011). 'Near wall haemodynamics:
modelling the glycocalyx'. MNF2011, 22-24 August
2011, Thessaloniki, Greece.
König, C.S.,
Ramachandran, S., González-Alonso, J., Atherton, M.,
Collins, M.W. (2013). ‘The Thermodynamics of Metabolism, Cardiovascular Performance and Exercise, in Health
and Diabetes: The Objective of Clinical Markers’. In:
Tuscany Endocrinology and Metabolism Conference, 4 – 6
April 2013, Pisa, Italy
Halls, J.A.T.,
Fomin, N., Greated, C.A., König, C.S., Collins, M. (2014). ‘Optical Coherence Tomography – Variations
on a Theme’. In Micro and Nano Flows 2014, 7-10 September 2014, London, UK
Papers
in Journals and Books
König, C.S.,
Clark, C., Mokhtarzadeh-Dehghan, M.R. (1999) 'Comparison
of flow in numerical and physical models of a ventricular assist device using
low and high viscosity fluids'. Journal of Engineering in Medicine,
Proceedings of the Institution of Mechanical Engineers Part H, Vol. 213, pp.
423-432.
König, C.S.
and Clark, C. (2001) 'Flow mixing and fluid residence times in a model of a
ventricular assist device'. Medical Engineering & Physics, 23, pp.
99-110.
König, C.S.
and Mokhtarzadeh-Dehghan, M.R. (2002) 'Numerical
study of buoyant plumes from a multi-flue chimney released into an atmospheric boundary
layer'. Atmospheric Environment, 36(24), pp. 3951-3962.
König, C.S.
& Sutherland, I.A. (2003) 'An investigation of the influence of the
gravity field on the interface of two immiscible liquids - a computational
study comparing prediction with experiment'. Journal for Liquid
Chromatography & Related Technologies, 26(9&10), pp. 1521-1535.
König, C.S.
& Sutherland, I.A. (2003) 'Numerical modelling of liquid-liquid flow
related to countercurrent chromatography (CCC) '.
In: Computational Methods in Multiphase Flow II, Eds. A.A. Mammoli
& C.A. Brebbia, WIT Press Southampton, Boston, Advances in Fluid MEchanics Series, 37, pp. 63-73, ISBN 1-85312-986-0.
König, C.S.
& Sutherland, I.A. (2005) 'The liquid-liquid interface under planetary
rotation '. In: Computational Methods in Multiphase Flow III, Eds. A.A. Mammoli & C.A. Brebbia, WIT Press Southampton, Boston,
Engineering Sciences Series, 50, pp. 317-326, ISBN 1-84564-030-6.
Mokhtarzadeh-Dehghan, M.R., König, C.S.,
Robins, A. (2006) 'Numerical study of two cooling tower turbulent plumes in
atmospheric cross flow '. In: Atmospheric Environment, 40, 3909-3923.
Zhao, G., Gao, H., Wu, J., Xu, S., Collins, M.W., Long, Q., König
&, C.S., Padhani, A.R. (2006) '2D numerical
simulation of the effect of antiangiogenic factors Angiostatin
and Endostatin on tumor-induced
angiogenisis'. Journal of Medical Biomechanics
(Chinese), 21(4), pp. 272-279.
Lui, D., Wu, J., Wei,
J.J., Long, Q., Collins, M.W., König &, C.S., Jiang, Y.P and' Padhani, A.R. (2006) 'Effect of injection strategy on
drug tranport in two-dimensional solid tumour'.
Journal of Medical Biomechanics (Chinese), 21(4), pp. 309-316.
König, C.S.
& Sutherland, I.A. (2007) 'Numerical model for the investigation of dual
flow in a spiral counter-current chromatography column '. J. of
Chromatography A, 1151, pp. 131-135. doi:10.1016/j.chroma.2007.02.070
Wu, J., Xu,
S.X., Long, Q., Collins, M.W., König, C.S., Zhao, G.P., Jiang, Y.P. and Padhani, A.R. (2007) '2D numerical simulation of tumor angiogenesis moving along random direction'.
Journal of Medical Biomechanics (Chinese) , 22(1), pp.
50-54.
Zhao, G., Wu,
J., Xu, S., Collins, M.W., Long, Q., König , C.S.,
Jiang, Y., Wang, J., Padhani, A.R. (2007). 'Numerical
simulation of blood flow and interstitial pressure in solid tumor
microcirculation based on tumor-induced angiogenisis '. Acta Mechanica Sinica (Springer),
23(5), 477-483.
Wu, J., Xu,
S., Long, Q., Collins, M.W., König, C.S., Zhao, G., Jiang, Y., Padhani, A.R. (2008). 'Coupled modelling of blood
perfusion in intravascular, interstitial spaces in tumor
microvasculature '. J. for Biomechanics, 41(5), pp. 996-1004.
Long, Q., Luppi, L., König, C.S., Rinaldo,
V., Das, S.K. (2008). 'Study of the collateral capacity of the circle of
Willis to patients with severe carotid artery stenosis by 3D computational
modelling '. J. of Biomechanics, 41(12), pp. 2735-2742.
König, C.S.
& Collins, M.W. (2009). 'Goethe, Eastlake and Turner: from colour theory
to art'. Int. J. of Design & Nature and Ecodynamics,
Vol. 4, No. 2, pp. 228-237.
König, C.S.
(2011). 'Correlations between art and CFD through colour and shape'.
Optics & Laser Technology, 43(2), pp. 348-357.
Halliday, I.,
Atherton, M., Care, C.M., Collins, M.W., Evans, D., Evans, P.C., Hose, D.R.,
Khir, A.W., König, C.S., Krams, R., Lawford, P.V., Lishchuck, S.V., Pontrelli, G., Ridger, V.,
Spencer, T.J., Ventikos, Y., Walker, D.C., Watton,
P.N. (2011). B 'Multi-scale interaction of particulate flow and the artery
wall'. Medical Engineering & Physics, 33(7), pp.840-848.
Pontrelli, G., König, C.S.,
Collins, M.W., Long, Q., Succi, S. (2011). 'Modelling
wall shear stress in small arteries using LBM and FVM: influence of the
endothelial wall profile '. Medical Engineering & Physics, 33(7), pp.
832-839.
van den Heuvel, R.N.A.M.,
König, C.S. (2011). 'Improved g-field calculations for coil planet centriguges '. J. Chromatography A, 1218(36), pp.
6038-6043.
Nayak,
A., König, C.S., Kishore, U., Evans, P.C. 'Regulation of endothelial
activation and vascular inflammation by shear stress '. In: Micro and
Nano Flow Systems for Bioanalysis, Series Bioanalysis,
Vol.2, 2013, Collins, Michael W.; König, Carola S. (Eds.), ISBN
978-1-4614-4375-9
Pontrelli, G., Halliday, I., Spencer, T.J., König, C.S., Collins, M.W.
(2013). ‘Modelling
the glycocalyx–endothelium–erythrocyte interaction in
the microcirculation: a computational study’,
Computer Methods in Biomechanics and Biomedical Engineering, pp. tba, http://dx.doi.org/10.1080/10255842.2013.799146
Collins,
M.W., König, C.S., Abbas, A., Jewkes, C., Jonas,
A.F., Ramachandran, S. (2014). ‘Association
between triglyceride and high-density lipoprotein cholesterol change following
fibrate therapy’, Diabetes Metab Syndr., Oct-Dec;8(4):212-5, doi: 10.1016/j.dsx.2014.09.004
Edited
Works & Guest Editorials
Editorial König, C.S. (2011). ‘Art and Color in
the Context of CFD: Towards a Better Engineering Design’, CFD Letters, Vol.
3(1), pp. ii-iv
Editorial Cutler D.F., Greated C.A., König, C.S.,
Collins, M.W. (2011). ‘Colour and Design
II: Colour in plants and animals – inspiration for design’, Optics &
Laser Technology, 43(2), p. 249, for Special
Issue: Colour and Design II: Colour in plants and animals – inspiration for
design, Optics & Laser Technology, Cutler D.F., Greated C.A., König, C.S.,
Collins, M.W. (Guest Editors), 43(2), March 2011, ISSN 0030-3992
Editorial König, C.S., Collins, M.W. (2011). Editorial, Med. & Eng. Phys.,
33(7), p. 799, for Special Issue:
Micro and Nano Flows 2009 – Biomedical Stream, König, C.S, Collins, M.W. (Eds),
Med. & Eng. Phys., 33(7), Sept. 2011, ISSN 1350-4533
Book Micro
and Nano Flow Systems for Bioanalysis, Series Bioanalysis, Springer,
Vol.2, 2013, Collins, Michael W.; König, Carola S. (Eds.), ISBN
978-1-4614-4375-9
Editorial König, C.S., Collins, M.W. (2014) 'Tackling scale in biomedical flows’. Biomechanics
and Modeling in Mechanobiology,
13(2), April , pp. 237-238, for Special
Issue: Tackling Scale in Biomedical Flows – König, C.S, Collins, M.W.
(Eds), Biomech Model Mechanobiol, 13(2), April 2014, ISSN 1617-7959 (Print)
1617-7940 (Online)
Book Kelvin, Thermodynamics and the
Natural World, WIT
Press, M.W. Collins, R.C. Dougal, C.S. K König, C.S., I.S. Ruddock,
in print
Editorial Carola
König, Alberto Redaelli, Dimitris Drikakis (2015). ‘Special issue: Micro and Nano Flows
(MNF2014)’, Microfluidics and Nanofluidics, in print
Contact Address
Dr. Carola S. König
Brunel Institute for Bioengineering
Brunel University
Uxbridge
UB8 3PH
Tel: +44 (0) 1895 266 915
Fax: +44 (0) 1895 274 608
Email: carola.koenig@brunel.ac.uk
Any comments
or queries can be sent to carola.koenig@brunel.ac.uk