Recovering metabolic pathways via optimization (with F.J. Planes), Bioinformatics, vol 23, 2007, 92-98
A metabolic pathway is a coherent set of enzyme catalysed biochemical reactions by which a living organism transforms an initial (source) compound into a final (target) compound. Some of the different metabolic pathways adopted within organisms have been experimentally determined. In this paper we show that a number of experimentally determined metabolic pathways can be recovered by a mathematical optimization model.
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J E Beasley