Systems Biology

Bioinformatics MRes module, 2007-2008

Module home page:

David Gilbert []

Systems Biology - module introduction
The amount and variety of biological data now available, together with techniques developed so far have enabled research in Bioinformatics to move beyond the study of individual biological components (genes, proteins etc) albeit in a genome-wide context to attempt to study how individual parts cooperate in their operation. Bioinformatics as a scientific activity has now moved closer to the area of Systems Biology which seeks to integrate biological data as an attempt to understand how biological systems function. By studying the relationships and interactions between various parts of a biological system it is hoped that an understandable model of the whole system can be developed.

Module contents

Related course readings Advanced Research Readings in Computer Science - Bioinformatics and Systems Biology (campus access only).

Timetable: Term 2, 2007-2008.
Friday 22nd February, Graham Kerr Seminar Room 10:30 till 11:30,
Lab room 101 Davidson Building 11:00 till 12:00 or 12:00 till 1:00

Wednesday 27th February, Boyd Orr Room 831, 10:00 till 11:00
Lab room 101 Davidson Building, 2:00 till 3:00

Thursday 28th February, Graham Kerr Library, 10:00 till 11:00
Lab 1 room 101 Davidson Building, 1:30 till 2:30

Friday 29th February, Bioinformatics Research Centre, Joseph Black Building, 10:00 till 11:00
Lab room 101 Davidson Building, 11:00 till 12:00

Course staff
Course lecturer: Professor David Gilbert
Course demonstrator: Xu Gu
Computing systems support officer: Robin Donaldson

Prior knowledge: The preceeding lectures in the Bioinformatics MRes course, and a basic background in biochemistry.

Slides / handouts

1: 22 Feb Systems Biology: Introduction Lab 1, Lab 1 extra - textmining
2: 27 Feb Networks: representation & static analysis Lab 2
3: 28 Feb Modelling dynamic behaviour Lab 3 (Xu Gu)
5: 29 Feb Modelling dynamic behaviour Lab 4;
extra! :-
BioNessie and MC2
Snoopy - Petri net tool

Readings and Course texts :

On-line resources: