Modelling of Signal Transduction cascades: Reading List

David Gilbert
Centre for Systems and Synthetic Biology
Brunel University, London, UK


Key
* Basic [essential]
** Advanced
*** Optional

Tools

  • * Snoopy

    Basic introduction

    (Basic)
    * W Marwan, C Rohr and M Heiner: Petri nets in Snoopy: A unifying framework for the graphical display, computational modelling, and simulation of bacterial regulatory networks. In Methods in Molecular Biology - Bacterial Molecular Networks, (Jv Helden, A Toussaint and D Thieffry, Eds.), Humana Press, pages 409-437, 2012

    (Advanced)
    ** MA Blätke, M Heiner, and W Marwan (2011), Tutorial - Petri Nets in Systems Biology. Otto von Guericke University Magdeburg, Magdeburg Centre for Systems Biology

    Basic framework

    (For a beginner:)
    * Monika Heiner, Robin Donaldson and David Gilbert (2010): Petri Nets for Systems Biology; In Symbolic Systems Biology: Theory and Methods, (MS Iyengar, Ed.), Jones & Bartlett Learning, LCC, pages 61-97. [Preprint]

    (Formal definitions, more advanced examples:)
    ** Monika Heiner, David Gilbert, and Robin Donaldson (2008), Petri Nets for Systems and Synthetic Biology. In M Bernardo, P Degano, and G Zavattaro (Eds.): Formal Methods for Systems Biology SFM 2008, Springer LNCS 5016, pp. 215-264, 2008. [Preprint]

    (Application to biological assays)
    *** Monika Heiner, Sebastian Lehrack, David Gilbert and Wolfgang Marwan (2009), Extended Stochastic Petri Nets for Model-Based Design of Wetlab Experiments in C Priami, RJ Back, I Petre (eds.): Computational models for cell processes; Trans. on Computational Systems Biology XI, Springer LNCS 5750, pp. 138-163. [Preprint]

    Modelling signal transduction pathways

    ** Rainer Breitling, David Gilbert, Monika Heiner, Richard Orton (2008). A structured approach for the engineering of biochemical network models, illustrated for signalling pathways. Briefings in Bioinformatics, 2008 9(5):404-42, doi:10.1093/bib/bbn026 [preprint]

    *** D. Gilbert, M. Heiner, R. Breitling, R. Orton (2010). Computational modelling of kinase signalling cascades in MAP Kinase Signaling Protocols, Rony Seger (Ed), Methods in Molecular Biology, 2010, Volume 661, Part 4, 369-384, DOI: 10.1007/978-1-60761-795-2_22. [PubMed]

    Further reading

    (Simple introduction)
    * Rainer Breitling, Robin Donaldson, David Gilbert, Monika Heiner (2010): Biomodel Engineering - From Structure to Behavior; (position paper) in C Priami et al. (eds.): Trans. on Computational Systems Biology XII, Springer LNCS 5945, pp. 1-12. [Preprint].

    *** M Heiner and D Gilbert: How Might Petri Nets Enhance Your Systems Biology Toolkit; In Proc. PETRI NETS 2011, LNCS 6709/2011, Springer, pages 17-37, DOI: 10.1007/978-3-642-21834-7_2. [Preprint]

    Wider reading

    (Link to volume with many examples of different modelling methodologies / examples)
    *** Corrado Priami, Rainer Breitling, David Gilbert, Monika Heiner, Adelinde M. Uhrmacher (Eds.) (2010). Transactions on Computational Systems Biology XII: Special Issue on Modeling Methodologies. Springer LNCS 5945, ISSN 0302-9743 (Print), 1611-3349 (Online).

    Rainer Breitling, Robin Donaldson, David Gilbert, Monika Heiner (2010): Biomodel Engineering - From Structure to Behavior; (position paper) in C Priami et al. (eds.): Trans. on Computational Systems Biology XII, Springer LNCS 5945, pp. 1-12. [Preprint].

    David Gilbert, Rainer Breitling, Monika Heiner, and Robin Donaldson (2009). An introduction to BioModel Engineering, illustrated for signal transduction pathways, 9th International Workshop, WMC 2008, Edinburgh, UK, July 28-31, 2008, Revised Selected and Invited Papers, Corne, D.; Frisco, P.; Paun, G.; Rozenberg, G.; Salomaa, A. (Eds.) LNCS Volume 5391, pp13-28 ISBN: 978-3-540-95884-0. [Preprint].

    David Gilbert, Monika Heiner and Sebastian Lehrack (2007). A Unifying Framework for Modelling and Analysing Biochemical Pathways Using Petri Nets In proceedings CMSB 2007 (Computational Methods in Systems Biology), Editors: M.Calder and S.Gilmore, Springer LNCS/LNBI 4695, pp. 200-216.

    David Gilbert and Monika Heiner, (2006). From Petri Nets to Differential Equations - an Integrative Approach for Biochemical Network Analysis, 27th International Conference on Application and Theory of Petri Nets and other models of concurrency (ATPN06), Turku, Finland, June 26-30, 2006. Proceedings; Editors: Susanna Donatelli, P. S. Thiagarajan; LNCS 4024 / 2006, pp. 181-200, ISBN: 3-540-34699-6 DOI: 10.1007/11767589 -->